The Northern California Comprehensive Sickle Cell Center is a longstanding collaborative effort between Children's Hospital & Research Center at Oakland and the University of California, San Francisco. It is in its 28th year of grant funding by the National Heart, Lung and Blood Institute as one of ten comprehensive sickle cell centers in the United States. The NCCSCC provides comprehensive care to over 1000 children and adults with sickle cell disease and other hemoglobinopathies in the San Francisco Bay area.

Advisory Boards: An external advisory board of scientists and clinicians review the scientific progress annually of the NCCSCC projects. A community advisory board, presently coordinated by Samuel Wallace and Wanda Williams, works with the center in implementing outreach, patient education, and review of center activities.